Fulham trail 2-1 in the tie ahead of the home leg, after defeat at Anfield earlier this month.
Adama Traore remains out with a niggling hamstring injury which he picked up while featuring for Fulham in a behind-closed-doors friendly in September.
It has heavily limited his game time in his first season at Craven Cottage since he joined as a free agent in the summer.
Joining Traore in the list of absentees for the biggest game of Fulham’s season are Alex Iwobi, Calvin Bassey and Fode Ballo-Toure, who are all in the Ivory Coast while competing at the Africa Cup of Nations.
Asked about team news ahead of hosting Liverpool, Fulham head coach Silva said: "Still the same — nothing different. Adama is still out. He’s not going to be involved in the squad list. All the other [unavailable] players are involved in the African Cup.
"All the others are available.”
Harry Wilson is only on the bench against his former side, while Tom Cairney gets the nod over Harrison Reed in midfield.
Starting XI: Leno, Castagne, Tosin, Diop, Robinson, Palhinha, Cairney, De Cordova-Reid, Pereira, Willian, Jimenez Subs: Rodak, Tete, Ream, Reed, Lukic, Francois, Wilson, Muniz, Vinicius
Time and date: 8pm GMT, Wednesday January 24, 2024
Venue: Craven Cottage
